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Accounting for Adverse Events Following Immunization in Economic Evaluation: Systematic Review of Economic Evaluations of Pediatric Vaccines Against Pneumococcus, Rotavirus, Human Papillomavirus, Meningococcus and Measles-Mumps-Rubella-Varicella
DiscussionAlthough (mild) AEFI were demonstrated for all five studied vaccines, only a quarter of reviewed studies accounted for these, mostly in an incomplete and inaccurate manner. We provide guidance on which methods to use to better quantify the impact of AEFI on both costs and health outcomes. Policymakers should be aware that the impact of AEFI on cost-effectiveness is likely to be underestimated in the majority of economic evaluations.
Source: PharmacoEconomics - February 21, 2023 Category: Health Management Source Type: research

Fight Aging! Newsletter, January 28th 2019
In this study, we show that calorie restriction is protective against age-related increases in senescence and microglia activation and pro-inflammatory cytokine expression in an animal model of aging. Further, these protective effects mitigated age-related decline in neuroblast and neuronal production, and enhanced olfactory memory performance, a behavioral index of neurogenesis in the SVZ. Our results support the concept that calorie restriction might be an effective anti-aging intervention in the context of healthy brain aging. Greater Modest Activity in Late Life Correlates with Lower Incidence of Dementia ...
Source: Fight Aging! - January 27, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

5 Year Old New Jersey Girl Died from the MMR Vaccine, Holly’s Law Created
Conclusion We leave you with words from Robin: “My family and I hope that Holly’s story will make a difference and help you realize that you must be aware of the risks of vaccinations, just as you make yourself aware of the risks of any medical procedure. We hope to make change, and one very important improvement must be that the pediatricians acknowledge that there are vaccine reactions, that moderate to serious and even fatal vaccine reactions do exist and occur at least 100 times more than is reported to the Vaccine Adverse Event Reporting System (VAERS).  We are still very disappointed and disgusted with the actio...
Source: vactruth.com - September 24, 2015 Category: Allergy & Immunology Authors: Augustina Ursino Tags: Augustina Ursino Human Top Stories adverse reactions Holly Marie Stavola Holly's Law MMR vaccine National Vaccine Injury Compensation Program (NVICP) Robin Stavola truth about vaccines Vaccine Death VAERS Source Type: blogs